Species Human Entrez 55816 | Human Mouse Ensembl ENSG00000101134 | |
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Aliases DOK5, C20orf180, IRS-6, IRS6, docking protein 5 External IDs MGI: 1924079 HomoloGene: 10195 GeneCards: DOK5 | ||
Docking protein 5 is a protein that in humans is encoded by the DOK5 gene.
Contents
Function
The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. In contrast to other DOK family proteins, this protein does not interact with RASGAP.
Interactions
DOK5 has been shown to interact with RET proto-oncogene.
References
DOK5 Wikipedia(Text) CC BY-SA