Species Human Entrez 23549 | Human Mouse Ensembl ENSG00000123992 | |
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Aliases DNPEP, ASPEP, DAP, aspartyl aminopeptidase External IDs MGI: 1278328 HomoloGene: 6110 GeneCards: DNPEP | ||
Aspartyl aminopeptidase is an enzyme that in humans is encoded by the DNPEP gene.
Contents
Function
The protein encoded by this gene is an aminopeptidase which prefers acidic amino acids, and specifically favors aspartic acid over glutamic acid. It is thought to be a cytosolic protein involved in general metabolism of intracellular proteins.
Model organisms
Model organisms have been used in the study of DNPEP function. A conditional knockout mouse line called Dnpeptm1e(EUCOMM)Wtsi was generated at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping
References
DNPEP Wikipedia(Text) CC BY-SA