Aliases DLX1, Dlx, Dlx-1 Ensembl ENSG00000144355 | Entrez 1745 | |
External IDs MGI: 94901 HomoloGene: 22558 GeneCards: DLX1 |
Function
This gene encodes a member of a homeobox transcription factor gene family similar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-β superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described.
References
DLX1 Wikipedia(Text) CC BY-SA