Entrez 55802 | Ensembl ENSG00000272886 | |
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Aliases DCP1A, HSA275986, Nbla00360, SMAD4IP1, SMIF, decapping mRNA 1A External IDs MGI: 1923151 HomoloGene: 10178 GeneCards: DCP1A | ||
mRNA-decapping enzyme 1A is a protein that in humans is encoded by the DCP1A gene.
Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway.
Interactions
DCP1A has been shown to interact with DCP2 and UPF1. It has also been shown to interact with GW182, a P-body marker.
References
DCP1A Wikipedia(Text) CC BY-SA