Species Human Entrez 51473 | Human Mouse Ensembl ENSG00000146038 | |
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Aliases DCDC2, DCDC2A, DFNB66, NPHP19, RU2, RU2S, doublecortin domain containing 2 External IDs OMIM: 605755 MGI: 2652818 HomoloGene: 9483 GeneCards: DCDC2 | ||
Doublecortin domain-containing protein 2 is a protein that in humans is encoded by the DCDC2 gene.
Contents
Function
This gene encodes a protein with two doublecortin peptide domains. This domain has been demonstrated to bind tubulin and enhance microtubule polymerization.
Clinical significance
Mutations in this gene have been associated with reading disability (RD), also referred to as developmental dyslexia.
Changes in the DCDC2 gene are frequently found among dyslexics. Altered alleles often occur among children with reading and writing difficulties. The gene appears to have a strong linkage with the processing of speech information when writing.
References
DCDC2 Wikipedia(Text) CC BY-SA