Species Human Entrez 8558 | Human Mouse Ensembl ENSG00000185324 | |
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Aliases CDK10, PISSLRE, cyclin-dependent kinase 10, cyclin dependent kinase 10 External IDs MGI: 2448549 HomoloGene: 55769 GeneCards: CDK10 | ||
Cell division protein kinase 10 is an enzyme that in humans is encoded by the CDK10 gene.
Contents
Function
The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation. Its function is limited to cell cycle G2-M phase. At least three alternatively spliced transcript variants encoding different isoforms have been reported, two of which contain multiple non-AUG translation initiation sites.
Interactions
Cyclin-dependent kinase 10 has been shown to interact with ETS2.
References
Cyclin-dependent kinase 10 Wikipedia(Text) CC BY-SA