Cyanide hydratase

In enzymology, a cyanide hydratase (EC 4.2.1.66) is an enzyme that catalyzes the chemical reaction

Hence, this enzyme has one substrate, formamide, and two products, cyanide and H₂O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is formamide hydro-lyase (cyanide-forming). Other names in common use include formamide dehydratase, and formamide hydro-lyase. This enzyme participates in cyanoamino acid metabolism.