Cusack is a surname. Notable people with the surname include:
Ann Cusack, American actress, daughter of Dick Cusack
Carmen Cusack, American musical theater actress and singer
Catherine Cusack, Irish actress, daughter of Cyril Cusack
Catherine Cusack (politician), Australian politician
Cyril Cusack, Irish actor
Dick Cusack, American actor and filmmaker
Donal Óg Cusack, Irish hurler
Dymphna Cusack, Australian writer
Joan Cusack, American actress, daughter of Dick Cusack
John Cusack, American actor and writer, son of Dick Cusack
John Cusack (Australian politician)
Joyce Cusack, American politician
Mary Frances Cusack, Irish nun and writer
Michael Cusack, Irish teacher and founder of the Gaelic Athletic Association
Niamh Cusack, Irish actress, daughter of Cyril Cusack
Robert Cusack, Australian swimmer
Sinéad Cusack, Irish actress, daughter of Cyril Cusack
Sorcha Cusack, Irish actress, daughter of Cyril Cusack
Thomas Cusack (disambiguation)