Compton is a surname. Notable people with the surname include:
Ann Compton, journalist
Arthur Compton, physicist and Nobel Prize winner, of the Compton effect, brother of Karl Taylor Compton and Wilson Martindale Compton, below
Barnes Compton, Maryland congressman and state officeholder
Charles H. Compton (1880–1966), American librarian and educator
Christian Compton, Justice of the Supreme Court of Virginia
Cliff Compton (born 1979), American professional wrestler, better known by his ring name, Domino
D.G. Compton, science fiction author
Denis Compton, England cricketer and footballer
Erik Compton, Norwegian-American professional golfer
F. E. Compton, publisher
Fay Compton, (1894–1974), English actress
Francis Compton (Conservative politician) (1824–1915), English lawyer and Conservative MP
Sir Francis Compton (c. 1629–1716), English soldier and MP for Warwick
Frances Snow Compton, a pseudonym used by Henry Adams
Henry Compton, Bishop of London
Henry Compton (actor), English actor
Ivy Compton-Burnett, English novelist
John Compton, leader of Saint Lucia United Workers Party
John Compton, London pipe & electronic organ maker
Karl Taylor Compton, physicist, one-time president of MIT, brother of Arthur Compton, above, Wilson Martindale Compton, below
Katie Compton, American bicycle racer
Leslie Compton, English footballer and cricketer
Lynn Compton, lead prosecutor in the Sirhan Sirhan trial and 101st Airborne World War II-veteran
Nick Compton, English cricketer
O'Neal Compton, American film and television actor
Patrick Compton, South African cricketer
Paul Compton, English footballer and football manager
Richard Compton, American actor
Richard G. Compton, chemist
Richard Compton (cricketer), South African cricketer
Robert Harold Compton, botanist
Spencer Compton, 1st Earl of Wilmington
Wayde Compton, Canadian writer
William Compton (courtier), lover of Henry VIII's notorious mistress, Anne Stafford; the two were prosecuted for adultery
Wilson Martindale Compton, fifth president of Washington State University, brother of Arthur Compton and Karl Taylor Compton, above