Cobalt precorrin 5B (C1) methyltransferase

Cobalt-precorrin-5B (C¹)-methyltransferase (EC 2.1.1.195, cobalt-precorrin-6A synthase, CbiD (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:cobalt-precorrin-5B (C¹)-methyltransferase. This enzyme catalyses the following chemical reaction

cobalt-precorrin-5B + S-adenosyl-L-methionine ⇌ cobalt-precorrin-6A + S-adenosyl-L-homocysteine

This enzyme catalyses the C-1 methylation of cobalt-precorrin-5B in the anaerobic pathway of adenosylcobalamin biosynthesis.