Suvarna Garge (Editor)

Clopamide

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Covid-19
ATC code  C03BA03 (WHO)
PubChem CID  2804
UNII  17S83WON0I
Molar mass  345.846 g/mol
CAS Number  636-54-4
ChemSpider  2702
CAS ID  636-54-4
Clopamide
AHFS/Drugs.com  International Drug Names

Clopamide (trade name Brinaldix) is a piperidine diuretic.

Contents

Medical vocabulary what does clopamide mean


Mechanism of action

Clopamide is categorised as a thiazide-like diuretic and works in similar way as the thiazide diuretics do. It acts in the kidneys, at the proximal convoluted tubule (PCT) of the nephron where it inhibits the sodium-chloride symporter. Clopamide selectively binds at the chloride binding site of the sodium-chloride symporter in the PCT cells on the luminal (interior) side and thus interferes with the reabsorption of sodium chloride, causing an equiosmolar excretion of water along with sodium chloride.

References

Clopamide Wikipedia


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