Cisneros is a Spanish surname. Notable people with the surname include:
Adriana Cisneros, Venezuelan journalist and the CEO and Vice Chairman of Cisneros Group.
Al Cisneros (contemporary), American stoner metal musician
Antonio Cisneros (born 1942), Peruvian poet
Baltasar Hidalgo de Cisneros (1758–1829), Viceroy of the Rio de La Plata
Diego Cisneros (1911–1980), Venezuelan businessman
Countess Eleonora de Cisneros, American opera singer
Francesc Antoni de la Dueña y Cisneros (1753–1821), Spanish Bishop of Urgell
Francisco Jiménez de Cisneros (1436–1517), Spanish cardinal and statesman; grand inquisitor
Gustavo Cisneros (born 1946), Venezuelan businessman
Patricia Phelps de Cisneros, philanthropist
Henry Cisneros (born 1947), American politician; mayor of San Antonio, Secretary of HUD
Ignacio Hidalgo de Cisneros (1896–1966), Spanish general of the Spanish Air Force
Melchor Liñán y Cisneros (1629–1708), Spanish prelate, colonial official, and viceroy of Peru
Pedro Treto Cisneros (1939–2013)
Rudy Cisneros (born 1981), American professional boxer
Sandra Cisneros (born 1954), American author and poet