EC number 3.1.1.41 ExPASy NiceZyme view | CAS number 52227-71-1 | |
In enzymology, a cephalosporin-C deacetylase (EC 3.1.1.41) is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are cephalosporin C and H2O, whereas its two products are deacetylcephalosporin C and acetate.
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is cephalosporin-C acetylhydrolase. Other names in common use include cephalosporin C acetyl-hydrolase, cephalosporin C acetylase, cephalosporin acetylesterase, cephalosporin C acetylesterase, cephalosporin C acetyl-esterase, and cephalosporin C deacetylase. This enzyme participates in penicillin and cephalosporin biosynthesis.
Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 1L7A, 1ODS, 1ODT, and 1VLQ.