Rahul Sharma (Editor)

Cell adhesion molecule 1

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Species
  
Human

Entrez
  
23705

Human
  
Mouse

Ensembl
  
ENSG00000182985

Cell adhesion molecule 1 ruomblcojpbiodtldtlimagesCM0043IPjpg

Aliases
  
CADM1, BL2, IGSF4, IGSF4A, NECL2, Necl-2, RA175, ST17, SYNCAM, TSLC1, sTSLC-1, sgIGSF, synCAM1, cell adhesion molecule 1

External IDs
  
MGI: 1889272 HomoloGene: 8641 GeneCards: CADM1

Cell adhesion molecule 1 is a protein that, in humans, is encoded by the CADM1 gene.

Contents

Model organisms

Model organisms have been used in the study of CADM1 function. A conditional knockout mouse line, called Cadm1tm1.2Brd was generated. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Twenty six tests were carried out on homozygous mutant mice and one significant abnormality was observed: males were infertile. Further analysis showed spermatogenesis had arrested in these mice.

Interactions

Cell adhesion molecule 1 has been shown to interact with EPB41L3.

References

Cell adhesion molecule 1 Wikipedia
(Text) CC BY-SA


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