Samiksha Jaiswal

Celiprolol

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ATC code  C07AB08 (WHO)
Biological half-life  5 hours
PubChem CID  2663
Bioavailability  30-70%
CAS Number  56980-93-9
Celiprolol
AHFS/Drugs.com  International Drug Names

Celiprolol (brand names Cardem, Selectol, Celipres, Celipro, Celol, Cordiax, Dilanorm) is a medication in the class of beta blockers, used in the treatment of high blood pressure. It has a unique pharmacology: it is a selective β1 receptor antagonist, but a β2 receptor partial agonist. It is also a weak α2 receptor antagonist.

In 2010 a clinical trial has suggested a use for this medication in the prevention of vascular complications of a rare inherited disease called vascular Ehlers–Danlos syndrome. This study demonstrated decreased incidence of arterial rupture or dissection (a specific type of arterial rupture in which the layers of the vessel separate prior to complete failure of the artery wall).

References

Celiprolol Wikipedia


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