Girish Mahajan

Cefditoren

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Trade names  Spectracef
MedlinePlus  a605003
CAS Number  104145-95-1
AHFS/Drugs.com  Monograph
ATC code  J01DD16 (WHO)
PubChem CID  9870843
Cefditoren

Cefditoren is a third-generation cephalosporin antibiotic for oral use. It is commonly marketed under the trade name Spectracef by Vansen Pharma Inc.

Contents

Cefditoren is also marketed under the name Meiact by Meiji Seika Pharma Co., Ltd.

Spectrum of bacterial susceptibility

Cefditoren has a broad spectrum of activity and has been used to treat bacterial infections of the skin and respiratory tract, including bronchitis, pneumonia, and tonsillitis. The following represents MIC susceptibility data for a few medically significant microorganisms.

  • Haemophilus influenzae: ≥0.063 - 0.25 μg/ml
  • Staphylcoccus aureus: 0.25 - >128 μg/ml (includes MRSA)
  • Streptococcus pyogenes: ≤0.004 - 2 μg/ml
  • Cefditoren is a broad-spectrum antibiotic against Gram-negative and Gram-positive bacteria, but does not have antibacterial activity against Pseudomonas aeruginosa.

    Indications

    Cefditoren is used to treat uncomplicated skin and skin structure infections, community-acquired pneumonia, acute bacterial exacerbation of chronic bronchitis, pharyngitis, and tonsillitis.

    Formulations

    Cefditoren is available as 200- and 400-mg tablets. It can be formulated as the prodrug cefditoren pivoxil.

    References

    Cefditoren Wikipedia


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