Routes of
administration Oral Biological half-life 1.8-8.6 h PubChem CID 441457 Molar mass 151.206 g/mol | ATC code A08AA07 (WHO) CAS Number 492-39-7 Formula C9H13NO | |
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Legal status AU: S4 (Prescription only)
CA: Schedule IV
DE: Anlage III (Prescription only)
UK: Class C
US: Schedule IV | ||
Cathine, also known as d-norpseudoephedrine and (+)-norpseudoephedrine, is a psychoactive drug of the phenethylamine and amphetamine chemical classes which acts as a stimulant. Along with cathinone, it is found naturally in Catha edulis (khat), and contributes to its overall effects. It has approximately 10-14% the potency of amphetamine.
Contents
Pharmacology
Like amphetamines, cathinone, and ephedrine, cathine acts as a norepinephrine releasing agent (NRA). It also acts as a dopamine releasing agent (DRA) to a lesser extent.
Chemistry
Cathine is one of the four stereoisomers of phenylpropanolamine (PPA).
Regulation
The World Anti-Doping Agency's list of prohibited substances (used for the Olympic Games among other athletic events) bars cathine in concentrations of over 5 micrograms per milliliter in urine. Cathine is a Schedule III drug under the Convention on Psychotropic Substances. In the United States, it is classified as a Schedule IV controlled substance.
In Australia, Cathine is officially a schedule 4 drug but is not yet available or approved for any use.
In Hong Kong, cathine is regulated under Schedule 1 of Hong Kong's Chapter 134 Dangerous Drugs Ordinance. Unlawful possession is punishable by severe fines and imprisonment.
