Entrez 5476 | Ensembl ENSG00000064601 | |
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External IDs OMIM: 613111 MGI: 97748 HomoloGene: 80163 GeneCards: CTSA | ||
Cathepsin A is an enzyme that is classified both as a cathepsin and a carboxypeptidase. In humans, it is encoded by the CTSA gene.
Contents
Function
This gene encodes a glycoprotein that associates with lysosomal enzymes beta-galactosidase and neuraminidase to form a complex of high-molecular-weight multimers. The formation of this complex provides a protective role for stability and activity. It is protective for β-galactosidase and neuraminidase.
Clinical significance
Deficiencies in this gene are linked to multiple forms of galactosialidosis.
Interactions
Cathepsin A has been shown to interact with NEU1.
References
Cathepsin A Wikipedia(Text) CC BY-SA