Aliases CATSPER2, CatSper2 Ensembl ENSG00000166762 | Entrez 117155 | |
External IDs MGI: 2387404 HomoloGene: 77423 GeneCards: CATSPER2 | ||
CatSper2, is a protein which in humans is encoded by the CATSPER2 gene. CatSper2 is a member of the cation channels of sperm family of protein. The four proteins in this family together form a Ca2+-permeant ion channel specific essential for the correct function of sperm cells.
Function
Calcium ions play a primary role in the regulation of sperm motility. This gene belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeat with six membrane-spanning segments and a predicted calcium-selective pore region. This gene is part of a tandem repeat on chromosome 15q15; the second copy of this gene is thought to be a pseudogene.
References
CatSper2 Wikipedia(Text) CC BY-SA