Castellano its a Spanish and Italian surname. Notable people with the surname include:
Abel Castellano, Jr. (born 1983), Venezuelan jockey
Dani Castellano (born 1987), Spanish footballer
Daniel Castellano (born 1972), Venezuelan journalist, writer and researcher
Fabio Castellano (born 1998), Italian professional footballer
Franco Castellano (1925 – 1999), Italian screenwriter and film director
Frank Castellano (born 1964), Commander of USS Bainbridge during hostage rescue
Javi Castellano (born 1987), Spanish professional footballer
Javier Castellano (born 1977), Venezuelan jockey
José María Castellano, (born 1947), Spanish businessman
Manuel Castellano (disambiguation), multiple people
Mateo Castellano (born 1996), Argentine footballer
Paco Castellano (born 1944), Spanish retired footballer
Paul Castellano (1915-1985), American mafia boss
Pedro Castellano (born 1970), Venezuelan baseball player
Ramón Castellano (born 1947), Spanish expressionist painter
Ramón José Castellano (1903–1979), Argentine Archbishop of Córdoba
Richard S. Castellano (1933–1988), American actor
Richie Castellano (born 1980), American bandleader, singer, songwriter and musician
Talia Castellano (1999–2013), American blogger
Tomás M. Castellano (1884-1921), Spanish poet
Torry Castellano (born 1979), drummer of The Donnas
Victor Castellano (born 1976), Venezuelan male weightlifter
Vittorio Castellano (1909–1997), Italian statistician