Casper is a surname. Notable people with the surname include:
Billy Casper (1931–2015), American golfer
Chris Casper (born 1975), English former footballer and football manager
Dave Casper (born 1951), American professional football player
Drew Casper, American film historian and theorist
Gerhard Casper (born 1937), ninth president of Stanford University
John Casper (born 1943), astronaut and U.S. Air Force colonel
Siegfried Jost Casper (born 1929), German biologist