Samiksha Jaiswal (Editor)

Caroxazone

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Pregnancycategory
  
?

ATC code
  
none

PubChem CID
  
29083

Routes ofadministration
  
Oral

CAS Number
  
18464-39-6

Molar mass
  
206.2 g/mol

Caroxazone httpsuploadwikimediaorgwikipediacommonsthu

Legal status
  
In general: ℞ (Prescription only)

How to pronounce caroxazone


Caroxazone (Surodil, Timostenil) is an antidepressant which was formerly used for the treatment of depression but is now no longer marketed. It acts as a reversible monoamine oxidase inhibitor (RIMA) of both MAO-A and MAO-B subtypes, with five-fold preference for the latter.

Contents

Synthesis

Synthesis starts by reductive amination of salicylaldehyde and glycinamide to give 3. The synthesis is completed by reaction with phosgene and NaHCO3.

References

Caroxazone Wikipedia


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