Formula C9H14N4O3 Melting point 253 °C | Molar mass 226.2324 g/mol Appearance Crystalline solid | |
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Carnosine an important anti aging nutrient gabriel cousens md
Carnosine (beta-alanyl--histidine) is a dipeptide molecule, made up of the amino acids beta-alanine and histidine. It is highly concentrated in muscle and brain tissues.
Contents
- Carnosine an important anti aging nutrient gabriel cousens md
- Carnosine the most effective anti aging supplement
- Atherosclerosis and aging
- Unreviewed studies claims
- References
Carnosine and carnitine were discovered by Russian chemist Vladimir Gulevich. Researchers in Britain, South Korea, Russia and other countries have shown that carnosine has a number of antioxidant properties that may be beneficial. Carnosine has been proven to scavenge reactive oxygen species (ROS) as well as alpha-beta unsaturated aldehydes formed from peroxidation of cell membrane fatty acids during oxidative stress. Carnosine is also a zwitterion, a neutral molecule with a positive and negative end.
Like carnitine, carnosine is composed of the root word carn, meaning flesh, alluding to its prevalence in animal protein. A vegetarian (especially vegan) diet provides less carnosine, compared to levels found in a more typical diet including meat.
Carnosine can chelate divalent metal ions.
Carnosine can increase the Hayflick limit in human fibroblasts, as well as appearing to reduce the telomere shortening rate. Carnosine is also considered as a geroprotector.
Carnosine the most effective anti aging supplement
Atherosclerosis and aging
Carnosine acts as an antiglycating agent, reducing the rate of formation of advanced glycation end-products (AGEs) (substances that can be a factor in the development or worsening of many degenerative diseases, such as diabetes, atherosclerosis, chronic renal failure, and Alzheimer's disease), and ultimately reducing development of atherosclerotic plaque build-up. Chronic glycolysis is speculated to accelerate aging, making carnosine a candidate for therapeutic potential.
Unreviewed studies & claims
The Professor Wang et al. clinical trial study called 'Use of carnosine as a natural anti-senescence drug for human beings' was carried out on 96 patients with cataracts of varying degrees of severity, which showed a success rate of 80% in advanced senile cataracts, and 100% in patients with mild to moderate cataracts, over the 6 months trial period.
Carnosine and blueberry extract together synergistically improved proliferation of human stem cells in vitro by 83%.
