Carbazole 1,9a dioxygenase

Carbazole 1,9a-dioxygenase (EC 1.14.12.22, CARDO) is an enzyme with systematic name 9H-carbazole,NAD(P)H:oxygen oxidoreductase (2,3-hydroxylating). This enzyme catalyses the following chemical reaction

9H-carbazole + NAD(P)H + H⁺ + O₂ ⇌ 2'-aminobiphenyl-2,3-diol + NAD(P)⁺

Carbazole 1,9a-dioxygenase catalyses the first reaction in the pathway of carbazole degradation.