Supriya Ghosh (Editor)

Carbamoyl phosphate

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
Formula
  
CH2NO5P2-

Molar mass
  
141.02 g/mol

Carbamoyl phosphate Question 6A Answer

Carbamoyl phosphate synthetase i deficiency medical condition


Carbamoyl phosphate is an anion of biochemical significance. In land-dwelling animals, it is an intermediary metabolite in nitrogen disposal through the urea cycle and the synthesis of pyrimidines.

Contents

Carbamoyl phosphate FileCarbamoylphosphatepng Wikimedia Commons

Medical vocabulary what does carbamoyl phosphate synthetase i activators mean


Production

Carbamoyl phosphate httpsuploadwikimediaorgwikipediacommonsthu

It is produced from bicarbonate, ammonia (derived from glutamine), and phosphate (from ATP). The synthesis is catalysed by the enzyme carbamoyl phosphate synthetase, as follows:

Carbamoyl phosphate Carbamoyl Phosphate Synthase I

  • HCO
    3
    + ATP → ADP + HO–C(O)–OPO2−
    3
    (carboxyl phosphate)
  • HO–C(O)–OPO2−
    3
    + NH3 + OHHPO2−
    4
    + O–C(O)NH2 + H2O
  • O–C(O)NH2 + ATP → ADP + H
    2
    NC(O)OPO2−
    3


  • Carbamoyl phosphate FileCarbamoylphosphatepng Wikimedia Commons

    References

    Carbamoyl phosphate Wikipedia