Samiksha Jaiswal (Editor)

CYP3A

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External IDs
  
Human
  
Mouse

n/a
  
n/a

Species
  
Human

Entrez
  
n/a

Aliases
  
cytochrome P450family 3subfamily ACYP3

Cytochrome P450, family 3, subfamily A, also known as CYP3A, is a human gene.

The CYP3A locus includes all the known members of the 3A subfamily of the cytochrome P450 superfamily of genes. These genes encode monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The CYP3A cluster consists of four genes:

  • CYP3A4
  • CYP3A5,
  • CYP3A7, and
  • CYP3A43.
  • The region also contains two pseudogenes:

  • CYP3A51P and
  • CYP3A52P,
  • as well as several extra exons which may or may not be included in transcripts produced from this region. Previously another CYP3A member, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4.

    References

    CYP3A Wikipedia


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