Species Human Entrez 1478 | Human Mouse Ensembl ENSG00000101811 | |
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Aliases CSTF2, CstF-64, cleavage stimulation factor subunit 2 External IDs MGI: 1343054 HomoloGene: 80171 GeneCards: CSTF2 | ||
Cleavage stimulation factor 64 kDa subunit is a protein that in humans is encoded by the CSTF2 gene.
This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs.
Interactions
CSTF2 has been shown to interact with CSTF3, SUB1, SYMPK, BARD1 and BRCA1.
References
CSTF2 Wikipedia(Text) CC BY-SA