Species Human Entrez 10815 | Human Mouse Ensembl ENSG00000168993 | |
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Aliases CPLX1, CPX-I, CPX1, complexin 1 External IDs MGI: 104727 HomoloGene: 21324 GeneCards: CPLX1 | ||
Complexin-1 is a protein that in humans is encoded by the CPLX1 gene.
Contents
Function
Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release.
Interactions
CPLX1 has been shown to interact with SNAP-25 and STX1A.
References
CPLX1 Wikipedia(Text) CC BY-SA