CP 132,484

CP-132,484 is a tryptamine derivative which acts as a potent and selective agonist for the 5-HT₂ family of serotonin receptors. It has reasonable selectivity for 5-HT_2A and 5-HT_2C subtypes over 5-HT_2B, but is only slightly selective for 5-HT_2A over 5-HT_2C. This compound and several related analogues have been shown to have ocular hypotensive activity in animal models, suggesting they may be useful for the treament of glaucoma.