Species Human Entrez 11316 | Human Mouse Ensembl ENSG00000105669 | |
 | ||
Aliases COPE, epsilon-COP, coatomer protein complex subunit epsilon External IDs MGI: 1891702 HomoloGene: 5254 GeneCards: COPE | ||
Coatomer subunit epsilon is a protein that in humans is encoded by the COPE gene.
Contents
Function
The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
Interactions
COPE (gene) has been shown to interact with COPA.
References
COPE (gene) Wikipedia(Text) CC BY-SA