Species Human Entrez 29883 | Human Mouse Ensembl ENSG00000198791 | |
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Aliases CNOT7, CAF1, Caf1a, hCAF-1, CAF-1, CCR4-NOT transcription complex subunit 7 External IDs MGI: 1298230 HomoloGene: 49011 GeneCards: CNOT7 | ||
CCR4-NOT transcription complex subunit 7 is a protein that in humans is encoded by the CNOT7 gene.
Contents
Function
The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
Interactions
CNOT7 has been shown to interact with:
References
CNOT7 Wikipedia(Text) CC BY-SA