Species Human Entrez 7122 | Human Mouse Ensembl ENSG00000184113 | |
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Aliases CLDN5, AWAL, BEC1, CPETRL1, TMVCF, claudin 5 External IDs MGI: 1276112 HomoloGene: 2459 GeneCards: CLDN5 | ||
Claudin-5 is a protein that in humans is encoded by the CLDN5 gene. It belongs to the group of claudins.
Contents
Function
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome.
Interactions
CLDN5 has been shown to interact with CLDN1 and CLDN3.
References
CLDN5 Wikipedia(Text) CC BY-SA