EC number 2.7.1.82 Human Mouse | Species Human Entrez 1119 | |
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Aliases CHKA, CHK, CK, CKI, EK, choline kinase alpha External IDs MGI: 107760 HomoloGene: 88575 GeneCards: CHKA | ||
Choline kinase alpha is an enzyme that in humans is encoded by the CHKA gene.
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene.
In melanocytic cells CHKA gene expression may be regulated by MITF.
References
CHKA Wikipedia(Text) CC BY-SA