CFU GM

Updated on Dec 17, 2024

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CFU-GM (or "GMP", for "granulocyte-macrophage progenitor") is a colony forming unit. It is derived from CFU-GEMM.

The "GM" stands for "granulocyte, monocyte".

It is the precursor for monoblasts and myeloblasts.

Production is stimulated by granulocyte macrophage colony-stimulating factor (GM-CSF).

Granulocytes

There is some controversy over which granulocytes derive from CFU-GM.

There is little disagreement that neutrophils come from CFU-GM.

Some sources state that basophils also derive from CFU-GM, but that eosinophils come from "CFU-Eos".

Other sources state that basophils do not derive from CFU-GM, but from a distinct CFU, titled "CFU-Baso".

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