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CFU GM

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TH H2.00.04.3.02009

CFU-GM

CFU-GM (or "GMP", for "granulocyte-macrophage progenitor") is a colony forming unit. It is derived from CFU-GEMM.

The "GM" stands for "granulocyte, monocyte".

It is the precursor for monoblasts and myeloblasts.

Production is stimulated by granulocyte macrophage colony-stimulating factor (GM-CSF).

Granulocytes

There is some controversy over which granulocytes derive from CFU-GM.

  • There is little disagreement that neutrophils come from CFU-GM.
  • Some sources state that basophils also derive from CFU-GM, but that eosinophils come from "CFU-Eos".
  • Other sources state that basophils do not derive from CFU-GM, but from a distinct CFU, titled "CFU-Baso".

    • References

    CFU-GM Wikipedia
    (Text) CC BY-SA