Species Human Entrez 80254 | Human Mouse Ensembl ENSG00000182923 | |
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Aliases CEP63, SCKL6, centrosomal protein 63 External IDs MGI: 2158560 HomoloGene: 11861 GeneCards: CEP63 | ||
Centrosomal protein of 63 kDa is a protein that in humans is encoded by the CEP63 gene. Several alternatively spliced transcript variants have been found, but their biological validity has not been determined.
Contents
Function
This gene encodes a protein with six coiled-coil domains. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. Recent computational analysis revealed pathogenic property of L61P point mutation in CEP63 protein that affected its native structural conformation.
Interactions
CEP63 has been shown to interact with DISC1, CEP152 and CDK1.
References
CEP63 Wikipedia(Text) CC BY-SA