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CDP glucose 4,6 dehydratase

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EC number
  
4.2.1.45

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
37259-55-5

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In the field of enzymology, a CDP-glucose 4,6-dehydratase is an enzyme that catalyzes the chemical reaction

Contents

CDP-glucose ⇌ CDP-4-dehydro-6-deoxy-D-glucose + H2O

Hence, this enzyme has one substrate, CDP-glucose, and two products, CDP-4-dehydro-6-deoxy-D-glucose and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. This enzyme participates in starch and sucrose metabolism. It employs one cofactor, NAD+.

Nomenclature

The systematic name of this enzyme class is CDP-glucose 4,6-hydro-lyase (CDP-4-dehydro-6-deoxy-D-glucose-forming). Other names in common use include:

  • cytidine diphosphoglucose oxidoreductase, and
  • CDP-glucose 4,6-hydro-lyase.

    • Structural studies

    As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1RKX and 1WVG.

    References

    CDP-glucose 4,6-dehydratase Wikipedia
    (Text) CC BY-SA


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