Species Human Entrez 113130 | Human Mouse Ensembl ENSG00000146670 | |
 | ||
Aliases CDCA5, SORORIN, cell division cycle associated 5 External IDs MGI: 1915099 HomoloGene: 49860 GeneCards: CDCA5 | ||
Sororin is a protein that in humans is encoded by the CDCA5 gene.
Contents
Function
Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase.
Clinical Significance
Transactivation of Sororin and its phosphorylation at Ser209 by ERK play an important role in lung cancer proliferation.
References
CDCA5 Wikipedia(Text) CC BY-SA