Rahul Sharma (Editor)

CD37

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Species
  
Human

Entrez
  
951

Human
  
Mouse

Ensembl
  
ENSG00000104894

CD37

Aliases
  
CD37, GP52-40, TSPAN26, CD37 molecule

External IDs
  
OMIM: 151523 MGI: 88330 HomoloGene: 20422 GeneCards: CD37

Leukocyte antigen CD37 is a protein that in humans is encoded by the CD37 gene.

Function

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.

References

CD37 Wikipedia