Entrez 951 | Ensembl ENSG00000104894 | |
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Aliases CD37, GP52-40, TSPAN26, CD37 molecule External IDs OMIM: 151523 MGI: 88330 HomoloGene: 20422 GeneCards: CD37 |
Function
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.
References
CD37 Wikipedia(Text) CC BY-SA