Species Human Entrez 51744 | Human Mouse Ensembl ENSG00000122223 | |
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Aliases CD244, 2B4, NAIL, NKR2B4, Nmrk, SLAMF4, CD244 molecule External IDs MGI: 109294 HomoloGene: 9493 GeneCards: CD244 | ||
Gene music using protein sequence of cd244 cd244 molecule natural killer cell receptor 2b4
CD244 (Cluster of Differentiation 244) is a human protein encoded by the CD244 gene. It is also known as Natural Killer Cell Receptor 2B4
This gene encodes a cell surface receptor expressed on natural killer cells (NK cells) (and some T cells) mediating non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. CD244 can also be expressed on non-lymphocytes such as eosinophils, mast cells and dendritic cells.
References
CD244 Wikipedia(Text) CC BY-SA