Entrez 4345 | Ensembl ENSG00000091972 | |
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Aliases CD200, CD200 molecule, MOX1, MOX2, MRC, OX-2 External IDs MGI: 1196990 HomoloGene: 4344 GeneCards: CD200 |
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OX-2 membrane glycoprotein, also named CD200 (Cluster of Differentiation 200) is a human protein encoded by the CD200 gene.
Contents
The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.
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References
CD200 Wikipedia(Text) CC BY-SA