Species Human Entrez 908 | Human Mouse Ensembl ENSG00000146731 | |
 | ||
Aliases CCT6A, CCT-zeta, CCT-zeta-1, CCT6, Cctz, HTR3, MoDP-2, TCP-1-zeta, TCP20, TCPZ, TTCP20, chaperonin containing TCP1 subunit 6A External IDs MGI: 107943 HomoloGene: 1336 GeneCards: CCT6A | ||
T-complex protein 1 subunit zeta is a protein that in humans is encoded by the CCT6A gene.
Contents
Function
This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.
Interactions
CCT6A has been shown to interact with PPP4C.
References
CCT6A Wikipedia(Text) CC BY-SA