Entrez 22948 | Ensembl ENSG00000150753 | |
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Aliases CCT5, CCT-epsilon, CCTE, HEL-S-69, TCP-1-epsilon, PNAS-102, chaperonin containing TCP1 subunit 5 External IDs MGI: 107185 HomoloGene: 6287 GeneCards: CCT5 | ||
T-complex protein 1 subunit epsilon is a protein that in humans is encoded by the CCT5 gene.
Contents
Function
This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Interactions
CCT5 (gene) has been shown to interact with PPP4C.
References
CCT5 (gene) Wikipedia(Text) CC BY-SA