Girish Mahajan (Editor)

CCNG1

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Aliases
  
CCNG1, cyclin G1, CCNG

Human
  
Mouse

Ensembl
  
ENSG00000113328

Species
  
Human

Entrez
  
900

CCNG1

External IDs
  
MGI: 102890 HomoloGene: 2995 GeneCards: CCNG1

Cyclin-G1 is a protein that in humans is encoded by the CCNG1 gene.

Contents

Function

The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene.

Interactions

CCNG1 has been shown to interact with:

  • Mdm2,
  • P16,
  • P53, and
  • PPP2R4.
  • References

    CCNG1 Wikipedia