Puneet Varma (Editor)

CCDC90B

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Species
  
Entrez
  
60492

Human
  
Ensembl
  
ENSG00000137500

Aliases
  
CCDC90B, MDS011, MDS025, coiled-coil domain containing 90B

External IDs
  
MGI: 1913615 HomoloGene: 23328 GeneCards: CCDC90B

Coiled coil domain containing 90B, also known as CCDC90B, is a protein encoded by the CCDC90B gene.

Contents

Gene

CCDC90B is located on chromosome 11 in humans. It is neighbored by:

  • PCF11, a mammalian pre-mRNA cleavage complex 2 protein
  • ANKRD42, ankyrin repeat protein involved with calcium ion bonding
  • BC070093
  • DLG2, a member of the membrane-associated guanylate kinase (MAGUK) family
  • Structure

    This protein is characterized by the presence of a domain of unknown function, DUF1640. This domain is a characteristic of the entire protein with the exception of the first twenty-three amino acid residues - MNSRQAWRLFLSQGRGDRWVSRP - which are a mitochondrial targeting site and cleaved.

    The protein has seven predicted alpha helices, a characteristic of coiled-coil proteins.

    Predicted Properties

    Molecular Weight: 26.72 kDa

    Isoelectric point: 7.5

    Transmembrane Helices: None

    Post-translation modifications:

    Cellular Location

    CCDC90B is predicted to be a mitochondrial protein with no transmembrane spans or segments. It is predicted to contain at least three specific phosphorylation sites: Protein Kinase C Phosphorylation sites, Casein Kinase II Phosphorylation sites, and cAMP/cGMP Dependant Phosphorylation sites.

    Function

    CCDC90B is not yet well understood by the scientific community.

    References

    CCDC90B Wikipedia


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