Species Human Entrez 25776 | Human Mouse Ensembl ENSG00000100211 | |
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Aliases CBY1, C22orf2, CBY, HS508I15A, PGEA1, PIGEA-14, PIGEA14, arb1, chibby homolog 1 (Drosophila), chibby family member 1, beta catenin antagonist External IDs MGI: 1920989 HomoloGene: 12514 GeneCards: CBY1 | ||
Protein chibby homolog 1 is a protein that in humans is encoded by the CBY1 gene.
Contents
Function
Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.
Interactions
CBY1 has been shown to interact with Beta-catenin.
References
CBY1 Wikipedia(Text) CC BY-SA