Species Human Entrez 10827 | Human Mouse Ensembl ENSG00000055147 | |
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Aliases FAM114A2, 133K02, C5orf3, family with sequence similarity 114 member A2 External IDs MGI: 1917629 HomoloGene: 10270 GeneCards: FAM114A2 | ||
C5orf3 (chromosome 5 open reading frame 3) is a gene on chromosome 5 in humans that encodes a protein FAM114A2. This protein has a function that is not well known. C5orf3 is, however, highly conserved in mammals with homologs both in fungi and plants.
Contents
Protein
The c5orf3 protein is 505 amino acids long with a molecular weight of 55.5 kdal and an isoelectric point of 4.66. It is predicted to stay in the nucleus after translation There is evidence that c5orf3 interacts with another protein of unknown function from chromosome 5, c5orf4 This protein is thought to include a P loop that suggests a role in ATP- and/or GTP-binding
Gene
The c5orf3 gene is located on chromosome 5 (5q31-33). This gene has 14 exons spanning through its sequence. The coding sequence is 2886 base pairs with a 5’ UTR of 94 base pairs and a 3’ UTR of 1273 base pairs. It is expressed at high levels in most tissues of the human body. It is also highly expressed in tissues in the human brain