Neha Patil (Editor)

Buparlisib

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ATC code
  
None

ChemSpider
  
17588300

Formula
  
C18H21F3N6O2

Molar mass
  
410.39 g/mol

PubChem CID
  
16654980

KEGG
  
D10584

3D model (Jmol)
  
Interactive image

Buparlisib fileselleckchemcomdownloadsstructBKM120chem

Buparlisib helps overcome endocrine resistance in metastatic breast cancer belle 2 trial results


Buparlisib (INN, codenamed BKM120) is an investigational small molecule orally-available pan-class I phosphoinositide 3-kinase inhibitor.

Contents

Results of the belle 3 study of buparlisib for advanced breast cancer


Clinical trials

In December 2015 it is reporting results for the phase III BELLE-2 clinical trial for advanced HR+/HER2 endocrine-resistant breast cancer. Encouraging results are reported in some sub-populations — e.g., some PI3K mutations.

References

Buparlisib Wikipedia