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Bruce H Lipshutz

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Name
  
Bruce Lipshutz

Role
  
Professor


Bruce H. Lipshutz wwwchemistryviewsorgSpringboardWebAppuserfiles

Books
  
Organometallics in Synthesis: Fourth Manual

Transitioning Organic Synthesis from Organic Solvents to Water


Bruce H. Lipshutz (born 1951) is an American chemist. He is a professor at the University of California, Santa Barbara.

Contents

Bruce H. Lipshutz wwwchemucsbedusitessecurelsitucsbeduchem

Designer Surfactants: How to Reduce Waste & Run Reactions in Water


Biography

Lipshutz received his undergraduate degree in chemistry from Binghamton University in 1973. His graduate work was supervised by Harry H. Wasserman at Yale. After a PhD degree in 1977, he spent two years at Harvard as a post-doctoral researcher in the group of Nobel Laureate E. J. Corey. Soon after, he accepted a position of Assistant Professor at UCSB rising to the ranks of Professor in 1987. He has received the Alfred P. Sloan Foundation Fellowship and the Camille & Henry Dreyfus Teacher-Scholar Award. In 2011 he was awarded Presidential Green Chemistry Award. He is Co-founder of Zymes LLC.

Reagents

  • Aqueous Micellar Catalysis using TPGS-750-M and Nok.
  • Sustainable Palladium catalysis.
  • 2-(Trimethylsilyl)ethoxymethyl chloride: hydroxyl protecting group, selectively cleaved with fluoride ion under mild conditions.
  • Di-(4-chlorobenzyl)azodicarboxylate (DCAD): recyclable and convenient alternative to diethylazodicarboxylate (DEAD) or diisopropyazodicarboxylate (DIAD) in Mitsunobu reaction.
  • Ligated copper hydride.
  • Heterogeneous catalysts: nickel-on-charcoal, copper-on-charcoal, nickel-in-graphite, copper+nickel-on-charcoal.
  • Methodologies

  • Higher order organocuprates (Lipshutz cuprates).
  • Chiral and achiral conjugate reductions.
  • References

    Bruce H. Lipshutz Wikipedia