Blythe is a surname. Notable people with the surname include:
Adam Blythe (born 1989), British road cyclist
Arthur Blythe (born 1940), American jazz alto saxophonist and composer
Colin Blythe (1879–1917), English cricketer
Daniel Blythe (born 1969), British author
Domini Blythe (1947–2010), British-born Canadian actress
Ernest Blythe (1889–1975), Irish politician
Geoffrey Blythe (died c. 1530), Bishop of Lichfield and Coventry
Geoffrey Blythe (divine)
George Donald Blythe, (1879-1911) Circumnavigator, Cape Horn, 1911
Gilbert Blythe
Jimmy Blythe (1901–1931), American jazz and boogie woogie pianist
John Blythe (disambiguation), several people
Mabel Blythe (1930–2004), Sri Lankan actress and singer
Matty Blythe, English rugby league player
Nils Blythe (born 1956), British journalist and Director of Communications at the Bank of England
Peter Blythe (1934–2004), British character actor
Randy Blythe (born 1971), vocalist of American heavy metal band Lamb of God and side-project band Halo of Locusts
Robert Blythe (actor), Welsh actor
Ronald Blythe (born 1922), English writer and editor
Samuel George Blythe
Stephanie Blythe, mezzo-soprano opera singer
Thomas H. Blythe, entrepreneur, pioneer of irrigation in the Colorado River valley. Blythe, California is named after him.
William Blythe (disambiguation), multiple people with the name, including:
William Jefferson Blythe III, better known as Bill Clinton, former President of the United States
Fictional characters:
Gilbert Blythe, fictional character in Lucy Maud Montgomery's Anne of Green Gables novel series