Samiksha Jaiswal (Editor)

Blasticidin S deaminase

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
EC number
  
3.5.4.23

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
54576-55-5

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a blasticidin-S deaminase (EC 3.5.4.23) is an enzyme that catalyzes the chemical reaction

blasticidin S + H2O deaminohydroxyblasticidin S + NH3

Thus, the two substrates of this enzyme are blasticidin S and H2O, whereas its two products are deaminohydroxyblasticidin S and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is blasticidin-S aminohydrolase.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1WN5 and 1WN6.

References

Blasticidin-S deaminase Wikipedia


Similar Topics